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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BECN1
All Species:
31.21
Human Site:
T388
Identified Species:
45.78
UniProt:
Q14457
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14457
NP_003757.1
450
51896
T388
E
E
V
E
K
G
E
T
R
F
C
L
P
Y
R
Chimpanzee
Pan troglodytes
XP_511522
450
51866
T388
E
E
V
E
K
G
E
T
R
F
C
L
P
Y
R
Rhesus Macaque
Macaca mulatta
XP_001111932
450
51890
T388
E
E
V
E
K
G
E
T
R
F
C
L
P
Y
R
Dog
Lupus familis
XP_537634
362
42279
R301
E
V
E
K
G
E
T
R
F
C
L
P
Y
R
M
Cat
Felis silvestris
Mouse
Mus musculus
O88597
448
51515
T386
E
E
V
E
K
G
E
T
R
F
C
L
P
Y
R
Rat
Rattus norvegicus
Q91XJ1
448
51538
T386
E
E
V
E
K
G
E
T
R
F
C
L
P
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514527
394
45783
A332
E
E
V
E
K
G
K
A
E
L
C
L
C
D
R
Chicken
Gallus gallus
Q5ZKS6
447
51416
T385
E
E
V
E
K
G
E
T
R
F
C
L
P
Y
R
Frog
Xenopus laevis
Q6GP52
445
51275
T383
E
E
V
E
K
G
D
T
G
F
C
L
P
Y
R
Zebra Danio
Brachydanio rerio
P13104
284
32704
E223
A
K
E
D
K
Y
E
E
E
I
K
V
L
T
D
Tiger Blowfish
Takifugu rubipres
NP_001032963
447
51199
T385
E
E
V
E
K
G
D
T
G
F
C
L
P
Y
R
Fruit Fly
Dros. melanogaster
Q9VCE1
422
48852
K360
Q
F
Q
K
E
V
E
K
R
D
T
E
F
L
L
Honey Bee
Apis mellifera
XP_392365
430
49618
K364
Q
F
K
E
Q
V
E
K
G
D
S
G
F
C
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786368
415
47747
R354
Q
L
E
E
E
V
E
R
G
D
S
S
F
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M367
517
58486
D421
A
D
F
A
N
S
K
D
Q
E
N
N
I
P
P
Baker's Yeast
Sacchar. cerevisiae
Q02948
557
63242
A478
D
E
S
S
M
N
N
A
N
D
V
E
N
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
78.8
N.A.
97.3
97.3
N.A.
76.8
91.7
88.6
20
81.1
49.1
56.4
N.A.
57.5
Protein Similarity:
100
99.7
99.7
79.5
N.A.
98
98.2
N.A.
81.5
94.6
94.8
36.4
89.5
67.7
69.3
N.A.
71.5
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
60
100
86.6
13.3
86.6
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
66.6
100
93.3
33.3
93.3
33.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
7
0
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
57
0
7
13
0
% C
% Asp:
7
7
0
7
0
0
13
7
0
25
0
0
0
7
7
% D
% Glu:
63
63
19
69
13
7
63
7
13
7
0
13
0
0
0
% E
% Phe:
0
13
7
0
0
0
0
0
7
50
0
0
19
0
0
% F
% Gly:
0
0
0
0
7
57
0
0
25
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% I
% Lys:
0
7
7
13
63
0
13
13
0
0
7
0
0
0
0
% K
% Leu:
0
7
0
0
0
0
0
0
0
7
7
57
7
7
19
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
7
7
7
0
7
0
7
7
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
50
7
7
% P
% Gln:
19
0
7
0
7
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
44
0
0
0
0
7
57
% R
% Ser:
0
0
7
7
0
7
0
0
0
0
13
7
0
7
0
% S
% Thr:
0
0
0
0
0
0
7
50
0
0
7
0
0
7
7
% T
% Val:
0
7
57
0
0
19
0
0
0
0
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
7
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _